Transparent — exactly as far as the evidence goes

Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling

Choi et al. (2014) · Mediators of InflammationPubMed ↗DOI ↗

SH003 induces apoptosis of DU145 prostate cancer cells by inhibiting ERK-involved pathway

Choi et al. (2016) · BMC Complementary and Alternative MedicinePubMed ↗DOI ↗

SH003 represses tumor angiogenesis by blocking VEGF binding to VEGFR2

Choi et al. (2016) · OncotargetPubMed ↗DOI ↗

SH003 selectively induces p73-dependent apoptosis in triple-negative breast cancer cells

Choi et al. (2016) · Molecular Medicine ReportsPubMed ↗DOI ↗

Synergistic Effect of SH003 and Doxorubicin in Triple-negative Breast Cancer

Woo et al. (2016) · Phytotherapy ResearchPubMed ↗DOI ↗

SH003 enhances paclitaxel chemosensitivity in MCF-7/PAX breast cancer cells through inhibition of MDR1 activity

Choi et al. (2017) · Molecular and Cellular BiochemistryPubMed ↗DOI ↗

SH003 reverses drug resistance by blocking signal transducer and activator of transcription 3 (STAT3) signaling in breast cancer cells

Seo et al. (2017) · Bioscience ReportsPubMed ↗DOI ↗

SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes

Choi et al. (2017) · OncotargetPubMed ↗DOI ↗

SH003-induced G1 phase cell cycle arrest induces apoptosis in HeLa cervical cancer cells

Lee et al. (2017) · Molecular Medicine ReportsPubMed ↗DOI ↗

Single-arm, open-label, dose-escalation phase I study to evaluate the safety of a herbal medicine SH003 in patients with solid cancer: a study protocol

Cheon et al. (2018) · BMJ OpenPubMed ↗DOI ↗

A Phase I Study to Evaluate the Safety of the Herbal Medicine SH003 in Patients With Solid Cancer

Cheon et al. (2020) · Integrative Cancer TherapiesPubMed ↗DOI ↗

Phase I study to evaluate the maximum tolerated dose of the combination of SH003 and docetaxel in patients with solid cancer: A study protocol

Cheon et al. (2020) · MedicinePubMed ↗DOI ↗